Alpha-Ketoglutarate (AKG) & Derivatives

 

Alpha-Ketoglutarate (AKG) and its derivatives are specialty raw materials engineered for dietary supplements, sports nutrition, functional foods, and selected animal nutrition applications.

 
  • Alpha-Ketoglutaric Acid (AKG)
    As a trusted global B2B ingredient manufacturer, we supply commercial-scale brand owners, contract manufacturers (CMOs), and distributors with stable batch consistency, full regulatory...
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  • Calcium Alpha-Ketoglutarate (Ca-AKG)
    Calcium Alpha-Ketoglutarate (Ca-AKG) is a high-purity, bioavailable mineral salt form of Alpha-Ketoglutarate (AKG). Specially engineered for dietary supplement manufacturers, CDMOs, and...
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  • Creatine Alpha-Ketoglutarate
    Creatine Alpha-Ketoglutarate (Creatine AKG) is a specialized compound combining creatine with alpha-ketoglutarate in a single raw material. Designed for sports nutrition brands, contract...
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  • L-Ornithine Alpha-Ketoglutarate (OAKG)
    L-Ornithine Alpha-Ketoglutarate (OAKG) is a stable salt synthesized from L-Ornithine and Alpha-Ketoglutaric Acid. It is widely used in sports nutrition, healthy aging products, functional foods,...
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  • Citrulline Alpha-Ketoglutarate
    Citrulline Alpha-Ketoglutarate (Citrulline AKG) combines L-Citrulline with Alpha-Ketoglutaric Acid into a high-purity, bioavailable functional ingredient. It is extensively utilized in sports...
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  • L-Arginine Alpha-Ketoglutarate (AAKG)
    L-Arginine Alpha-Ketoglutarate (AAKG) is a high-purity compound engineered for sports nutrition brands, contract manufacturers (CMOs/CDMOs), and ingredient distributors. Formulated specifically...
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Product Overview & Applications

 

Product

Abbreviation

Key Characteristics & Target Applications

Alpha-Ketoglutaric Acid

AKG

Free acid form; ideal for formulations requiring uncomplexed AKG and specific pH levels.

Calcium Alpha-Ketoglutarate

Ca-AKG

Bioavailable calcium salt; widely evaluated for healthy aging, longevity, and bone health blends.

L-Arginine Alpha-Ketoglutarate

AAKG

Combines L-arginine and AKG; popular in pre-workout powders and nitric oxide support formulations.

L-Ornithine Alpha-Ketoglutarate

OAKG

Synergistic amino acid complex; targeted for recovery, cellular health, and specialized nutrition.

L-Glutamine Alpha-Ketoglutarate

Glutamine AKG

Stable glutamine compound; suited for gut health, muscle recovery, and post-workout products.

Citrulline Alpha-Ketoglutarate

Citrulline AKG

High-performance combination; designed for enhanced pump, endurance, and advanced pre-workouts.

Creatine Alpha-Ketoglutarate

Creatine AKG

Highly soluble creatine complex; optimized for athletic performance and strength formulations.

 

 
Formulating with AKG: Key Considerations

Dietary Supplements & Longevity:

Ca-AKG and free AKG are preferred for capsules, tablets, and longevity complexes due to stable mineral profiles and dose control.

Sports & Performance Nutrition:

AAKG, Citrulline AKG, Glutamine AKG, and Creatine AKG simplify manufacturing by supplying dual active nutrients in a single ingredient.

Functional Foods & Beverages:

Formulators must evaluate solubility speed, thermal processing tolerance, and taste-masking requirements. Micronized powder options are recommended for instantized drink blends.

Animal Nutrition:

Specific feed-grade specifications are available depending on target species, dosage format, and local regulatory allowances.

 

 

Quality Assurance & Technical Documentation

Essential Specifications Validated
Chemical Identifiers: CAS Number, Molecular Formula, Molecular Weight


Physical Properties: Appearance, Particle Size (e.g., 80 Mesh, Micronized), Bulk Density, Tap Density


Chemical Integrity: Assay/Purity (via HPLC/Titration), Loss on Drying, Heavy Metals, Microbilogical Profile


Quality & Compliance Documentation Available
Batch-Specific Certificate of Analysis (COA)


Safety Data Sheet (SDS / MSDS) & TDS


Certifications: ISO9001, cGMP, HACCP, Kosher, Halal, Non-GMO, Allergen-Free Statement

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Selection Guide for Procurement Teams

 

Target Requirement

Recommended AKG Form

Primary Evaluation Criteria

Pure, unbound AKG

Alpha-Ketoglutaric Acid

Acidity (pH), free acid assay, pure solubility

Combined with Calcium

Calcium Alpha-Ketoglutarate

Calcium content %, AKG assay %, heavy metals

Nitric Oxide / Pre-workout

L-Arginine Alpha-Ketoglutarate

Molar ratio, powder flowability, dissolution rate

Specialized Amino Synergy

L-Ornithine Alpha-Ketoglutarate

Active ratio balance, purity, stability

Recovery & Gut Health

L-Glutamine Alpha-Ketoglutarate

Glutamine content, shelf-life stability

Endurance & Hydration

Citrulline Alpha-Ketoglutarate

Citrulline-to-AKG balance, taste, moisture control

Strength & Bioavailability

Creatine Alpha-Ketoglutarate

Creatine equivalence, water solubility

 

Packaging, Minimum Orders (MOQ) & Sampling
 
 

Standard Packaging:

25 kg/fiber drum with dual PE inner bags. Customized packaging options are available upon request.

 
 
 

Shelf Life & Storage:

24-month shelf life when stored sealed in a cool, dry place away from direct light and excessive humidity.

 
 
 

Sample Policy:

Verified laboratory samples with lot-matching COAs are available for evaluation prior to bulk production orders.

 

 

 

FAQ

 

Q: What is Alpha-Ketoglutarate (AKG)?

A: Alpha-Ketoglutarate, also known as 2-oxoglutaric acid, is an intermediate of the tricarboxylic acid cycle and is involved in amino acid metabolism. It can be supplied as free-form AKG or as different derivative forms.

Q: What is the difference between AKG and Calcium AKG?

A: AKG refers to the free acid form of alpha-ketoglutarate, while Calcium AKG is a calcium salt of alpha-ketoglutarate. They have different chemical forms and should be specified separately during raw material procurement.

Q: Which AKG derivative should I choose for sports nutrition?

A: The appropriate derivative depends on the formulation objective. AAKG, Citrulline AKG, and Creatine AKG can be evaluated when the formulation requires AKG together with arginine, citrulline, or creatine.

Q: What specifications should I check before purchasing AKG?

A: Buyers should review the exact chemical form, CAS Number, assay or purity, appearance, moisture, solubility, test method, grade, packaging, storage conditions, and shelf life.

Q: Can AKG be supplied in bulk?

A: Yes. AKG and its derivatives can be supplied as bulk raw materials for further manufacturing. MOQ, packaging, lead time, shelf life, and documentation should be confirmed for the specific product and order quantity.

Q: What documents should I request from an AKG supplier?

A: Common procurement documents include a COA, product specification, SDS/MSDS, batch or lot information, packaging details, and storage recommendations.

Q: Can I request an AKG sample before placing a bulk order?

A: A sample can be requested for formulation evaluation and supplier qualification. Buyers can compare the sample with the agreed specification and conduct internal testing before approving commercial supply.

We're professional alpha-ketoglutarate (akg) & derivatives manufacturers and suppliers in China, specialized in providing the best custom service. We warmly welcome you to buy bulk high quality alpha-ketoglutarate (akg) & derivatives in stock here from our factory.

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