L-Beta-Aminoisobutyric Acid (L-BAIBA)
L-Beta-Aminoisobutyric Acid (L-BAIBA), also known as S-BAIBA or L-3-Aminoisobutyric Acid, is a non-protein beta-amino acid and the specific S-enantiomer of beta-aminoisobutyric acid.
Identified by CAS No. 4249-19-8, L-BAIBA is widely specified in commercial formulations and academic research where stereochemical purity and exact chemical identity are required.
Key Product Specifications
|
Parameter |
Technical Specification |
Test Method / Reference |
|
Product Name |
L-Beta-Aminoisobutyric Acid |
-- |
|
Synonyms |
L-BAIBA, S-BAIBA, L-3-Aminoisobutyric Acid |
-- |
|
CAS No. |
4249-19-8 |
-- |
|
Molecular Formula |
C4H9NO2 |
-- |
|
Molecular Weight |
103.12 g/mol |
-- |
|
Configuration |
Defined S / L Enantiomer |
Optical Rotation / Chiral HPLC |
|
Physical Form |
Crystalline Powder |
Visual |
|
Appearance |
White to off-white powder |
Visual |
|
Assay (Purity) |
>= 98.0% (Dry Basis) |
HPLC |
|
Optical Purity |
>= 98.0% e.e. |
Chiral HPLC |
|
Loss on Drying |
<= 1.0% |
USP <731> / 105°C |
|
Residue on Ignition |
<= 0.5% |
USP <281> |
|
Heavy Metals |
<= 10 ppm |
ICP-MS |
|
Packaging |
1 kg/bag, 25 kg/fiber drum, or custom |
Commercial standard |
|
Storage |
Store in tightly sealed containers in a cool, dry place away from light |
Per Safety Data Sheet (SDS) |
Why the L-Isomer Matters
Chemical Identity: L-BAIBA refers specifically to the S-enantiomer (CAS No. 4249-19-8).
Risk Mitigation: Specifying the CAS number alongside the L/S configuration prevents accidental procurement of non-stereospecified or racemic (DL-beta-aminoisobutyric acid) mixtures.
Specification-Driven Quality Control
Chemical Identification: Authenticated via standard spectrum comparison (FTIR / NMR / Mass Spec).
Assay Verification: Quantification using validated HPLC methodology to ensure consistent active compound density (>= 98.0%).
Chiral Control: Stereochemical purity evaluated via Chiral HPLC to guarantee minimal presence of the unwanted enantiomer.
Impurity Profiling: Routine testing for heavy metals, moisture content, and residual solvents to comply with international dietary supplement standards.
Targeted Applications
Sports Nutrition & Exercise Physiology Research
L-BAIBA has drawn significant attention in modern sports science as an exercise-induced muscle metabolite (myokine signaling molecule). It is commonly evaluated in research-backed pre-workout, endurance, and metabolic support formulations.
Nutraceutical Development
Formulators utilize L-BAIBA in premium health products targeting:
- Metabolic health and efficiency
- Lipid metabolism pathways
- Healthy aging and cellular wellness formulations
Biochemical & Laboratory R&D
Essential for analytical reference testing, metabolic pathway studies, and specialty biochemical assays requiring an enantiomerically pure beta-amino acid standard.
Supplier Qualification Checklist & B2B Solutions
Chemical Identity: Explicitly defined as L-BAIBA / S-BAIBA with CAS No. 4249-19-8.
Purity Standard: Numerical assay requirement clearly stated (>= 98.0%) with HPLC testing protocol.
Quality Documentation: Batch-specific COA, GHS-compliant SDS, and TDS available for technical review.
Material Consistency: Sample evaluation matches commercial bulk production parameters.
Supply Readiness: Verified packaging options, commercial lead times, and industrial QA traceability.
Commercial & Supply Chain Details
Technical Documentation: COA, SDS, TDS, Certificate of Origin (COO), and Process Flowcharts provided upon request.
Supply Capacity: Commercial bulk quantities and pilot-scale batches available.
Packaging Options: 1 kg aluminum foil bags; 25 kg cardboard fiber drums with double PE inner liners.
Sample Policy: R&D samples available upon request for lab testing and formulation verification.
FAQ
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