Tetrahydrocurcumin (4HC) CAS 36062-04-1 | High-Purity Wholesale Cosmetic & Nutraceutical Ingredient

Tetrahydrocurcumin (4HC) is a hydrogenated, light-colored derivative of curcuminoid. Designed specifically for cosmetics, personal care, and functional formulations where traditional yellow curcumin causes unwanted discoloration.

Tetrahydrocurcumin Product Specifications

Parameter	Specification Criteria
Product Name	Tetrahydrocurcumin
Abbreviation	4HC
CAS No.	36062-04-1
INCI Name	Tetrahydrocurcumin
Molecular Formula	C21H24O6
Molecular Weight	372.41 g/mol
Appearance	White to off-white powder
Identification	Passes HPLC test
Assay (HPLC)	Standardized per agreed specification (e.g., ≥ 95.0%)
Loss on Drying	Controlled per approved specification
Residual Curcuminoids	Controlled & quantified per approved specification
Heavy Metals	Meets international safety limits (Lead, Arsenic, Cadmium, Mercury)
Microbiological Limits	Complies with cosmetic/nutraceutical standards
Particle Size	Customizable based on formulation requirements

What Makes Tetrahydrocurcumin Different from Curcumin?

Consideration	Conventional Curcumin	Tetrahydrocurcumin (4HC)
Chemical Structure	Standard Curcuminoid	Reduced (Hydrogenated) Curcuminoid
Powder Color	Intense Yellow to Orange-Yellow	White to Off-White
Color Impact on Formulations	Strong yellow tint (can limit light formulas)	Minimal color impact
Antioxidant Potential	High	High
Primary Formulation Focus	Oral supplements, dark/colored formulations	Skin brightening, anti-aging serums, light lotions
Key QC Parameters	Assay, color intensity, heavy metals	Assay, residual curcuminoids, color impact, batch stability

Recommended Cosmetic & Personal Care Applications

Facial Serums & Concentrates: Daily brightening and anti-aging treatments.

Light-Colored Creams & Lotions: Day creams, night lotions, and moisturizing bases.

Spot-Care & Targeted Treatments: Blemish and hyperpigmentation formulas.

Sun Care & After-Sun Care: Soothing, antioxidant-rich formulations.

Formulation & Solubility Guidelines

Solvent Selection: Ethanol, glycols, or oil-phase incorporation depending on system design.

Processing Conditions: Monitor processing temperatures and pH stability during emulsification.

Small-Scale Bench Testing: Always perform pilot compatibility testing before commercial scale-up.

Regulatory Compliance & Quality Certifications

We support global brand owners and contract manufacturers (CMOs/CDMOs) with full compliance documentation:

EU Cosmetic Regulation (EC) No 1223/2009: Compliant for cosmetic formulation.

REACH Registered / Compliant: Ready for European Union import.

Manufacturing Quality: Produced in ISO / GMP certified facilities.

Ethical Statements: Cruelty-Free, Non-GMO, and Vegan suitable options available upon request.

Technical Documentation Available for Buyer Qualification

Certificate of Analysis (COA): Batch-specific testing results for incoming QC validation.

Technical Data Sheet (TDS): Complete physical, chemical, and storage guidelines.

Safety Data Sheet (SDS): Updated OSHA / GHS compliant safety and handling instructions.

Method of Analysis (MOA): HPLC test methodology details.

Standard Qualification & Purchasing Workflow

Define Your Target: Specify required quantity, target assay, and application needs.

Review Documentation: Download our TDS, SDS, and sample specification sheets.

Bench Sample Testing: Evaluate color compatibility, solubility, and dispersion in your formulation.

Final Commercial Order: Confirm batch availability, lead times, and tailored packaging requirements.

FAQ

Q: What is Tetrahydrocurcumin (4HC)?

A: Tetrahydrocurcumin is a reduced curcuminoid with CAS No. 36062-04-1. It is used as an ingredient for cosmetic, personal care, nutraceutical and research applications, subject to the applicable product specification and regulatory requirements.

Q: What is the difference between Tetrahydrocurcumin and Curcumin?

A: Tetrahydrocurcumin is a reduced form of curcumin and is generally much lighter in color. This makes it relevant to formulations where the strong yellow appearance of conventional curcumin is undesirable.

Q: What is the typical appearance of Tetrahydrocurcumin?

A: Commercial Tetrahydrocurcumin is commonly supplied as a white to off-white powder. The exact appearance should be confirmed against the approved specification and batch COA.

Q: Is Tetrahydrocurcumin water soluble?

A: Conventional Tetrahydrocurcumin should not automatically be described as freely water soluble. Its solubility depends on the solvent, concentration, particle characteristics and formulation system.

Q: How is Tetrahydrocurcumin assay tested?

A: HPLC is commonly used for identification and assay. Depending on the approved specification, additional testing can include moisture, residual curcuminoids, heavy metals, microbiological parameters and particle size.

Q: What are the main applications of Tetrahydrocurcumin?

A: Typical application areas include cosmetic and personal care formulations, antioxidant-focused skincare, nutraceutical development where permitted, and research or formulation development.

Q: Can I request a sample before placing a bulk order?

A: Sample evaluation is recommended when the buyer needs to verify appearance, analytical characteristics, handling, dispersion or formulation compatibility before moving to commercial quantities.

Q: What documents are available for Tetrahydrocurcumin?

A: Typical B2B documentation includes a batch-specific COA, TDS, SDS and product specification. Additional analytical or technical documents can be discussed according to the intended application and destination market.

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Tetrahydrocurcumin (4HC)